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2025, Vol: 4, Issue: 2
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Original Article
Online Published: 30 Oct 2024
 


Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome

Samir Derouiche, Malika Kherraz, Nour El Houda Chekima, Roufaida Allahoum.


Abstract
Background and Aims: More than 1.55 million women of reproductive age have polycystic ovary syndrome (PCOS) in the world; PCOS is an important disease threatens public health, linked to psychological, metabolic, and reproductive problems. The aim of our work was an evaluation of some risk factors, oxidative stress and Cardiovascular Risk among PCOS Women in El-Oued region. Methods: Our risk factor study was conducted on a group of 200 women who were diagnosed by specialized doctors (100 healthy and 100 polycystic ovaries), with 50 women volunteering to provide blood and saliva samples to study the blood glucose, Atherogenic index, lipids profile, hematological and oxidative stress markers. Results: About risk factors study, our results showed that the high levels of Psychological distress, Menstrual fluctuation and year of taking pills are the most dangerous factors (OR=3.11; OR=9.205; OR=5.940) respectively. Our result demonstrated a significant increase (P > 0.05) in blood glucose, total cholesterol, Triglycerides, VLDL, Atherogenic index and sedimentation rate, MDA and SOD levels and a significant decreased (P > 0.01) in HDL, WBC (P < 0.000), MCV (P < 0.05) HGB, RBC, CMH, CMH level in women with PCOS patients as compared to controls. Conclusions: In conclusion, several social and nutritional factors contributed to the spread and development of PCOS in El-Oued region. In addition to a change in blood components, lipid profile Atherogenic index and their relationship to oxidative stress, which contributes to metabolic syndrome development and the occurrence of cardiovascular complication in women with PCOS.

Key words: PCOS, Risk factors, Metabolic syndrome, Cardiovascular event, Oxidative stress


 
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How to Cite this Article
Pubmed Style

Derouiche S, Kherraz M, Chekima NEH, Allahoum R. Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. J Med Res Rev. 2024; 3(2): 37-44. doi:10.5455/JMRR.20240809073855

Web Style

Derouiche S, Kherraz M, Chekima NEH, Allahoum R. Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. https://www.wisdomgale.com/jmrr/?mno=214892 [Access: June 05, 2025]. doi:10.5455/JMRR.20240809073855

AMA (American Medical Association) Style

Derouiche S, Kherraz M, Chekima NEH, Allahoum R. Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. J Med Res Rev. 2024; 3(2): 37-44. doi:10.5455/JMRR.20240809073855


Vancouver/ICMJE Style

Derouiche S, Kherraz M, Chekima NEH, Allahoum R. Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. J Med Res Rev. (2024), [cited June 05, 2025]; 3(2): 37-44. doi:10.5455/JMRR.20240809073855


Harvard Style

Derouiche, S., Kherraz, . M., Chekima, . N. E. H. & Allahoum, . R. (2024) Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. J Med Res Rev, 3 (2), 37-44. doi:10.5455/JMRR.20240809073855


Turabian Style

Derouiche, Samir, Malika Kherraz, Nour El Houda Chekima, and Roufaida Allahoum. 2024. Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. Journal of Medical Research and Reviews, 3 (2), 37-44. doi:10.5455/JMRR.20240809073855


Chicago Style

Derouiche, Samir, Malika Kherraz, Nour El Houda Chekima, and Roufaida Allahoum. "Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome." Journal of Medical Research and Reviews 3 (2024), 37-44. doi:10.5455/JMRR.20240809073855


MLA (The Modern Language Association) Style

Derouiche, Samir, Malika Kherraz, Nour El Houda Chekima, and Roufaida Allahoum. "Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome." Journal of Medical Research and Reviews 3.2 (2024), 37-44. Print. doi:10.5455/JMRR.20240809073855


APA (American Psychological Association) Style

Derouiche, S., Kherraz, . M., Chekima, . N. E. H. & Allahoum, . R. (2024) Study of socio-clinical risk factors and assessment of metabolic syndrome and Risk of Cardiovascular Events in Patients With polycystic ovary syndrome. Journal of Medical Research and Reviews, 3 (2), 37-44. doi:10.5455/JMRR.20240809073855


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