Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.

Sunday Charles Olaogun; Mayowa Akinpelumi Taiwo; Akinleye Stephen Akinrinde; Amos Ayodele Oladipupo; Emmanuel Adeoye Adenaike

doi:10.5455/JRVS.20260528082240

Original Article
Online Published: 24 Jul 2026

J Res Vet Sci. 2026; 6(3): 260-271

doi: 10.5455/JRVS.20260528082240

Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.

Sunday Charles Olaogun, Mayowa Akinpelumi Taiwo, Akinleye Stephen Akinrinde, Amos Ayodele Oladipupo, Emmanuel Adeoye Adenaike.

Abstract
Background and Aim: Peste des Petits Ruminants (PPR) is an economically important clinical disease of small ruminants in Nigeria with it devastated socio-economic consequences. Data on extent of derangement in the levels of oxidative stress biomarkers in PPRV infected goats have not been well established among Nigerian indigenous goats. This study establishes and compares the levels of biomarkers of oxidative stress parameters in Peste des Petits Ruminants virus (PPRV)-infected and non-infected goat breeds in Nigeria.
Method: Blood samples were aseptically collected through the jugular veins of goats manifesting clinical symptoms of PPR using plain sterile test tubes. Test was carried out to confirm the PPR diagnosis using the SZ FINDE® PPRV Antibody Rapid Test kit following the manufacturer's procedure. Sera were harvested and then stored at -20°C until analyzed for oxidative stress biomarkers using standard methods.
Results: Findings reveal 29.6% positivity and 70.4% negativity to PPRV in all goats sampled. Increased levels of serum oxidants, including malondialdehyde, hydrogen peroxide, and advanced oxidation protein products in PPRV-infected compared to non-infected with p-values of 0.000773, 0.023219, and 0.001261, respectively were observed. Whereas significant decreased in serum Glutathione S-transferase in PPRV-infected compared to non-infected goats with 0.023 ± 0.0032 and 0.027 ± 0.0066, respectively, with a p-value of 0.015037 was observed.
Conclusion: Red Sokoto breed, female and young goats, showed more positivity for PPRV compared to other breeds, male and adult’s goat respectively. Significant variations were recorded, with the infected group showing higher MDA, H2O2, and AOPPs levels and lower NO concentration.

Key words: Oxidants, antioxidants, PPR, goats, Ibadan.

	ARTICLE TOOLS
	Abstract
	PDF Fulltext
	How to cite this article
	Citation Tools
	Related Records
	Articles by Sunday Charles Olaogun Articles by Mayowa Akinpelumi Taiwo Articles by Akinleye Stephen Akinrinde Articles by Amos Ayodele Oladipupo Articles by Emmanuel Adeoye Adenaike
	on Google
	on Google Scholar

How to Cite this Article

Pubmed Style

Olaogun SC, Taiwo MA, Akinrinde AS, Oladipupo AA, Adenaike EA. Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. J Res Vet Sci. 2026; 6(3): 260-271. doi:10.5455/JRVS.20260528082240

Web Style

Olaogun SC, Taiwo MA, Akinrinde AS, Oladipupo AA, Adenaike EA. Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. https://www.wisdomgale.com/jrvs/?mno=322518 [Access: July 30, 2026]. doi:10.5455/JRVS.20260528082240

AMA (American Medical Association) Style

Olaogun SC, Taiwo MA, Akinrinde AS, Oladipupo AA, Adenaike EA. Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. J Res Vet Sci. 2026; 6(3): 260-271. doi:10.5455/JRVS.20260528082240

Vancouver/ICMJE Style

Olaogun SC, Taiwo MA, Akinrinde AS, Oladipupo AA, Adenaike EA. Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. J Res Vet Sci. (2026), [cited July 30, 2026]; 6(3): 260-271. doi:10.5455/JRVS.20260528082240

Harvard Style

Olaogun, S. C., Taiwo, . M. A., Akinrinde, . A. S., Oladipupo, . A. A. & Adenaike, . E. A. (2026) Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. J Res Vet Sci, 6 (3), 260-271. doi:10.5455/JRVS.20260528082240

Turabian Style

Olaogun, Sunday Charles, Mayowa Akinpelumi Taiwo, Akinleye Stephen Akinrinde, Amos Ayodele Oladipupo, and Emmanuel Adeoye Adenaike. 2026. Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. Journal of Research in Veterinary Sciences, 6 (3), 260-271. doi:10.5455/JRVS.20260528082240

Chicago Style

Olaogun, Sunday Charles, Mayowa Akinpelumi Taiwo, Akinleye Stephen Akinrinde, Amos Ayodele Oladipupo, and Emmanuel Adeoye Adenaike. "Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.." Journal of Research in Veterinary Sciences 6 (2026), 260-271. doi:10.5455/JRVS.20260528082240

MLA (The Modern Language Association) Style

Olaogun, Sunday Charles, Mayowa Akinpelumi Taiwo, Akinleye Stephen Akinrinde, Amos Ayodele Oladipupo, and Emmanuel Adeoye Adenaike. "Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.." Journal of Research in Veterinary Sciences 6.3 (2026), 260-271. Print. doi:10.5455/JRVS.20260528082240

APA (American Psychological Association) Style

Olaogun, S. C., Taiwo, . M. A., Akinrinde, . A. S., Oladipupo, . A. A. & Adenaike, . E. A. (2026) Comparison of Oxidative stress biomarkers between Peste des petits Ruminants’ infected and non-infected goats in Ibadan, Nigeria.. Journal of Research in Veterinary Sciences, 6 (3), 260-271. doi:10.5455/JRVS.20260528082240